This issue highlights the many challenges to controlling the scourge of Viral Hepatitis in Africa: poor public and political awareness, lack of accurate data for action, vaccination coverage, diagnosis and treatment; proffers approaches to address the challenges, including the dire need to increase the awareness and training of health care workers on hepatitis B and C.
Nwabuaku, et al. demonstrated a high prevalence of minimal hepatic encephalopathy (HE) in subjects with chronic liver disease. Infection and occult GI bleeding were significant risk factors for HE in this cohort. Adoption of cognitive evaluation may allow early identification of this liver de-compensation thus enabling a more aggressive preventative strategy.
In patients with Sickle cell anaemia, intrahepatic sickling and iron overload may be responsible for liver enzyme derangements, irrespective of hepatitis status as documented by Odeghe, et al. Other interesting articles in this edition include the experience of a Hepato-biliary Surgical Unit and their laudable efforts to establish laparoscopic cholecystectomy for the management of acute cholecystitis and a case report describing the rare gastro-duodenal Crohn’s disease in a young man with upper GI bleeding.
— Lesi, OA
For far too long, viral hepatitis has been neglected by the international community, policy makers, governments, health care providers and the public. Although the virus was discovered over 50 years ago and an effective vaccine has been available for more than 20 years, the complications of chronic ...
— Agbugui JO, Osaigbovo EO and Ibadin EI
Background and Objectives: Transmission of Hepatitis B virus (HBV) from patients to health care personnel (HCP) can occur following occupational exposures. Vaccination is effective in disease prevention. The study aimed to determine the level of uptake of HBV vaccine among a cohort of Nigerian surgi...
— Odeghe EA, Lesi OA and Otegbayo JE
Background: Elevation of serum transaminases is common in sickle cell anaemia (SCA) patients and the causes are multiple and may be due to the underlying sickling state or complications of multiple blood transfusions.
Objectives: To determine the prevalence of raised serum transaminases in stable p...
— Nwabuaku OJ, Onyekwere CA and Ogun SA
Background: Minimal Hepatic Encephalopathy (MHE) reflects the earliest stage of HE, its identification is important to retard its progression.
Objectives: To determine the prevalence of MHE amongst patients with chronic liver disease (CLD) in a tertiary hospital in Lagos State.
Materials and Metho...
— Yusuf M, Alikah FO, and Okokhere PO
Crohn’s disease is a chronic idiopathic inflammatory condition of the gastrointestinal tract, which rarely affects the oesophagus and stomach together. The usual sites of involvement are the terminal ileum and proximal colon. It is rarer still for gastric Crohn’s disease to present for t...
— Ngim OE, Ekong ME, Marwa AD and Ndoma-Egba RE
The aim of this study was to evaluate the pattern of presentation of patients who had cholecystectomy in a dedicated Hepato-Pancreato-Biliary (HPB) Surgery unit of this facility and the benefit of laparoscopic cholecystectomy over conventional open cholecystectomy. This is a five year retrospective ...
The Nigerian Journal of Gastroenterology and Hepatology, is a quarterly publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), which publishes original research on the biology and diseases of the Gut, Liver, Pancreas, Peritoneum and Spleen both in humans and experimental animal models.