Volume 8

Vol. 8 No. 2

It is with great pleasure that I introduce our respected readers to this issue of NJGH. The editorial board has put together an assortment of thought-provoking papers, including a review article, original articles, a case report and abstracts presented at the 2016 Annual Scientific Conference of SOGHIN in Lagos.

There is a saying that “the more things change, the more they stay the same”. Few months ago, the Rome IV criteria for functional gastrointestinal disorders (FGID)1 was launched to replace Rome III which had been subsisting for ten years. Some of the changes that were made are actually not new, with the result that a see-saw phenomenon seems to be playing out. The review article in this issue of NJGH titled “Concepts and controversies in disorders of upper gastrointestinal tract” highlights some of the unresolved issues in functional and non-functional gastrointestinal disorders.

The discovery of Helicobacter pylori over 3 decades ago2 was a milestone in the understanding of acid-peptic disorders. Contributing to the subject, Abdel, et al used a polymerase chain reaction (PCR) technique to determine the association between various gastrointestinal symptoms and Helicobacter pylori infection of the stomach. Their findings are contained in this issue. In the same vein, Ndububa, et al contributed an article titled: The pattern of gastritis and Helicobacter pylori colonization of the stomach in Nigerian patients with dyspepsia.

Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections are major contributors to morbidity and mortality globally especially in Africa. Also, featured in this issue is a study by Adesina, et al which describes selected laboratory values in pregnant women with HIV-HCV infection.

Review Article

CONCEPTS AND CONTROVERSIES IN DISORDERS OF UPPER GASTROINTESTINAL TRACT

— Nwokediuko SC, Ijoma U, Obienu O and Anigbo G

Abstract:
The upper gastrointestinal tract is one part of the digestive system where tremendous innovations and advancements in knowledge have been recorded in the last several decades. The discovery of Helicobacter pylori by Warren and Marshal in 1983 and the introduction of Rome process for the classificati...

Original Article

HELICOBACTER PYLORI AND UPPER DIGESTIVE DISEASES - DIAGNOSIS THROUGH REAL TIME PCR

— Serme AK, Compaore NI, Compaore R, Djigma F, Somda KS, Diarra B, Coulibaly A, Zohoncon T, Obiri-Yeboah D, Sombie AR, Bougouma A and Simpore J

Abstract:
Objective: Helicobacter pylori, which has been designated by the WHO as type I carcinogen, has a global prevalence of over 50%. The aim of this study was to determine the association between this bacterium and upper gastrointestinal problems in an endoscopy unit in Ouagadougou, using a molecular dia...

Original Article

PATTERN OF GASTRITIS AND HELICOBACTER PYLORI COLONIZATION OF THE STOMACH IN NIGERIAN PATIENTS WITH DYSPEPSIA

— Ndububa DA, Adekanle O, Omonisi AE, Ijarotimi O, Alatise OI, Ojo OS and Agbakwuru EA

Abstract:
Objective: Helicobacter pylori infection of the stomach causes chronic active gastritis. The pattern of gastritis is related to the disease outcome. This study aimed to determine the predominant gastritis pattern in Nigerian dyspeptic patients with a view to predicting gastroduodenal disease outcome...

Original Article

EFFECT OF HEPATITIS C VIRUS INFECTION ON SELECTED LABORATORY VALUES IN PREGNANT WOMEN WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION

— Adesina OA, Akinyemi JO, Michael OS, Fayemiwo SA, Awolude OA, Ogunbosi BO, Kuti MA and Adewole IF

Abstract:
Background and Objectives: Both hepatitis C and Human Immunodeficiency viruses affect laboratory indices. The objective of this study was to describe the impact of both viruses on laboratory indices among 1,821 HIV-positive pregnant women.<br /> <br /> Methods: This was a cross-sectional retrospecti...

Original Article

JUVENILE POLYPOSIS SYNDROME PRESENTING AS INTUSSUSCEPTION IN A MALNOURISHED CHILD: A CASE REPORT

— Badmos KB, Elebute OA, Obadofin OO, Alakaloko MF and Abdulkareem FB

Abstract:
We report a rare case of juvenile polyposis syndrome (JPS) in a 5 year old girl who was admitted into the emergency room on account of acute intestinal obstruction secondary to ileo-colic intussusception. Prior to the admission, she has had repeated blood transfusion in the referring hospital follow...

About Us

The Nigerian Journal of Gastroenterology and Hepathology, is a quarterly publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), which publishes original research on the biology and diseases of the Gut, Liver, Pancreas, Peritoneum and Spleen both in humans and experimental animal models.

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