Volume 6

Vol. 6 Nos. 1 & 2

In this edition, the importance of multi-disciplinary team (MDT) approach for cancer management is featured. Oguntunde et. al, highlight the need to set up and sustain MDTs as an essential cancer- management protocol and discuss the opportunities for and challenges against its use in Nigeria. Drug induced hepatotoxicity of anti-tuberculosis therapy in subjects with HIV infection is a real clinical challenge and is evaluated by Nnabuchi et al. The role of various commonly used local herbs in the development of hepatotoxicity has always been a moot point but unproven phenomenon. Odigwe et al, convincingly highlight the role of hepatotoxicity of Pausinystalia yohimbe bark extract (Burantashi), a local herb commonly used as an aphrodisiac.

In the newly established SOGHIN News Corner, we showcase the occasion of 2014 World Hepatitis Day Events, which took place in more than 28 locations in Nigeria. Community hepatitis testing was carried out in volunteers in 27 centers nationwide and over 7,500 people were screened for Hepatitis B and C. This opened up a previously unexplored opportunity for SOGHIN to carry out nationwide hepatitis data capture as part of a nationwide prevalence study.

Review Article

MULTIDISCIPLINARY TEAM (MDT) APPROACH TO MANAGEMENT OF MALIGNANT DISEASES: A REVIEW

— Oguntunde O, Orah N, and Rotimi O.

Abstract:
Background: Multidisciplinary Team meetings (MDTs) in cancer management emphasize collaborative decision making and treatment planning among core members of the specialties relevant to an index case, who come together to share their knowledge and make recommendations for an ‘all-inclusive&...

Original Article

SUB-ACUTE HEPATOTOXICITY OF PAUSINYSTALIA YOHIMBE BARK EXTRACT (BURANTASHI) IN MALE ALBINO RATS (RATTUS NOVERGICUS)

— Odigie BE and Osula FO

Abstract:
Background: Burantashi (Yohimbe in English)(Pausinystalia yohimbe=Corynanthe yohibi) (Family, Rubiaceae) is a true aphrodisiacused as a possible treatment for organic, psychogenic and substance induced erectile impotence and other male sexual dysfunctions. It increases blood flow to erectile tissues...

Original Article

THE PREVALENCE OF DRUG INDUCED HEPATOTOXICITY AMONG HIV POSITIVE AND HIV NEGATIVE PATIENTS WITH PULMONARY TUBERCULOSIS IN BENIN CITY, NIGERIA

— Nnabuchi CV, Omuemu CE, Lesi OA and Ndububa DA

Abstract:
Introduction: Drug induced hepatotoxicity is a recognized problem associated with the anti-tuberculosis (anti-TB) chemotherapy and is of great concern especially in this era of HIV infection.<br /> <br /> Objectives: To obtain the prevalence of hepatotoxicity due to anti-TB medications in HIV positi...

Case Reports

SCLEROSING CHOLANGITIS WITH ULCERATIVE COLITIS IN A NIGERIAN WOMAN

— Owoseni OO, Lesi OA, Adeyomoye AA, Awolola NA and Anunobi CC

Abstract:
Primary Sclerosing Cholangitis (PSC) is a relatively rare cause of chronic liver disease worldwide. It presents as chronic cholestasis associated with jaundice and pruritus. We report a middle aged Nigerian woman who presented with cholestatic jaundice and diagnosed with PSC with concurrent ulcerati...

About Us

The Nigerian Journal of Gastroenterology and Hepathology, is a quarterly publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), which publishes original research on the biology and diseases of the Gut, Liver, Pancreas, Peritoneum and Spleen both in humans and experimental animal models.

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