Nigerian Journal of Gastroenterology and Hepatology

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The NIGERIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, abbreviated as Nig. J. Gastroenterol. Hepatol. is a quarterly publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN) which publishes original research on the biology and diseases of the Gut, Liver, Pancreas, Peritoneum and Spleen both in humans and experimental animal models.

Vol. 10 No. 1

June 2018

The Nigerian Journal of Gastroenterology and Hepatology (NJGH) is the official publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN). It publishes original research, reviews, randomized trials, and case reports on the biology and diseases of the gut, liver, pancreas, peritoneum and spleen in humans and experimental animal models. This year (2018) is the 10th year of existence of the Journal. This is a significant milestone and the opportunity should be seized to reflect on the objectives behind the founding of this Journal, the accomplishments so far recorded, and plans for improvement.

It would be appropriate to first present a brief historical account of the circumstances that necessitated the formation of SOGHIN and eventual founding of NJGH. The Society for Gastroenterology and Hepatology in Nigeria is the product of the historic merger of the Association for Study of the Liver (ASLIN) and the Nigerian Chapter of West African Society for Gastroenterology (WASOG), in Port Harcourt in September 2007 with Professor B.J. Bojuwoye as the pioneer president. West African Society for Gastroenterology was the older of the two progenitor associations, but prior to the merger, WASOG had been inactive for many years; a situation that resulted partly from the brain drain that hit the Nigerian medical sector in the 1980s and 1990s.

A group of scholars and medical professionals at Obafemi Awolowo University Teaching Hospital, Ile-Ife led by Professor Olusegun Ojo and Professor Dennis Ndububa rose to the occasion to close the void in this very important medical subspecialty. They started by forming the “Ife Liver Study Group”which provided the template for the formation of Nigeria Association for the Study of the Liver (NASL); the name was later changed to ASLIN. Exactly one year after the formation of SOGHIN (2008), its official publication (NJGH) was launched.

Nigerian Journal of Gastroenterology and Hepatology is published twice a year (June and December) and has maintained this frequency in a timely and uninterrupted fashion since inception. Each issue features a minimum of 3 original research articles. Review articles on topics of interest in gastroenterology are also frequently featured. Nigerian Journal of Gastroenterology and Hepatology is currently listed in African Journals Online (AJOL) and the process of getting it into Pubmed has been activated. It is hoped that this would be achieved within the next few years. The Journal is also aspiring to get listed in Thompson Reuters and its impact factor rating.

Professor Jesse Otegbayo was the pioneer Editor-in-Chief of NJGH. He laid a very solid foundation for the Journal and has continued to make his services available to succeeding Editorial Boards to ensure that the Journal continues to make progress. His dedication to duty, intellectual prowess and scholarly exploits have continued to inspire the younger ones.

I would like to seize this opportunity to thank the immediate past editor, Professor Funmi Lesi and all former and current members of the Editorial Board for their hard work, diligence and cooperation. The modest achievements the Journal has recorded would not have been possible without them. Tribute should also be paid to the pioneer and successive leaderships of SOGHIN. Right from inception, NJGH has remained a priority project of SOGHIN with the result that the financial support required for seamless operations of the Journal has never been in short supply. I am particularly grateful to the present Executive Council of SOGHIN led by Professor Musa Borodo for being favourably disposed towards the growth of the Journal. Our Publishers, Samdavies Publishers under the leadership of Mr. `Bukola Oyejide have been a great asset to the Journal. Their help made our job much easier.

Finally, I would like to thank our authors and reviewers for their support. Peer review remains an effective mechanism of ensuring that quality articles are published. Readers of this Journal are encouraged to take advantage of our timely review and personalised review process by sending their manuscripts to NJGH.

Vol. 9 No. 2

December 2017

The Editorial Board of Nigerian Journal of Gastroenterology and Hepatology (NJGH) presents to our esteemed readers Volume 9, Number 2 of our Journal. This edition is a potpourri of hot topics drawn from various aspects of gastroenterology and hepatology.

Chronic gastritis is one of the most common clinico-pathologic entities encountered in gastroenterology practice but to date, it has no universally accepted classification system. The Sydney system was a watershed in the search for a system that would meet the needs of clinicians, pathologists and researchers as this system made it possible to integrate information on topographical distribution and morphological parameters in order to make aetiopathogenetic inferences. The search for a better classification system continues and in this issue of Nigerian Journal of Gastroenterology and Hepatology (NJGH) a discourse of some classification systems that have emerged in the post-Sydney era is featured.

Despite the introduction of new techniques in endoscopic hemostasis and potent acid suppressants in the last 3 decades, the mortality of peptic ulcer bleeding remains high. To underscore the importance of this subject, an article on the use of Forrest scoring system for risk stratification in patients with peptic ulcer bleeding from South West Nigeria is included in this issue.

Nigeria is one of the countries of the world with high prevalence of irritable bowel syndrome. Also featured is a paper on dietary associations in irritable bowel syndrome in Lagos residents.

Debate over the status of medicine as an Art or Science continues to gather steam. One thing that is incontrovertible is that it is common to encounter some overlaps between subjects that are traditionally grouped as science or humanities. For instance, the methods of inquiry in both fields are so similar. To drive this point home, a new perspective in the control of Hepatitis B virus infection is introduced in this issue of NJGH in the form of an original research. The main thrust of the study is the use of theatrical activities as interventions in improving awareness and knowledge of Hepatitis B virus.

One of the challenges faced by hepatologists in the management of inflammatory diseases of the liver is the assessment of the fibrotic evolution of chronic hepatitis. The diagnostic accuracy of some indirect markers of liver fibrosis in patients with chronic hepatitis B and C is one of the articles featured in this edition

Other interesting packages in this edition are case reports and abstracts presented at the 10th Annual Scientific Conference of Society for Gastroenterology and Hepatology in Nigeria (SOGHIN) held at Ado-Ekiti, July 25-28, 2017.

Enjoy your reading and feel free to send your observations and suggestions to our Editorial Office.

Vol. 9 No. 1

June 2017

About one year ago, the Nigerian Finance Minister officially admitted that the country’s economy had entered recession. Prior to this declaration, the health sector was notorious in parading some of the worst health indices in the world.

The recession has undoubtedly compounded an already bad situation. The purchasing power of Nigerians has nosedived amidst unpaid workers’ salaries. Qualitative healthcare is beyond the reach of most people, as people no longer patronize hospitals, self-medication is at an all-time high and quacks now take advantage of the situation. Cost of medical equipment, consumables and drugs has increased to incredible levels due in part to scarcity of foreign exchange. Shortage of vaccines is now common place in Nigeria.

The harsh economic climate is taking a huge toll on the digestive health of Nigerians. Hepatitis B virus (HBV) infection is a major public health issue, affecting about 20 million Nigerians, with great morbidity and mortality. This disease is vaccine-preventable but the prevalent disruption in vaccine supplies especially in parts of the country ravaged by insurgency is a cause for great concern. The consequences of not immunizing Nigerian children against HBV in 2017 are unimaginable, considering the fact that infections acquired in childhood tend to run a protracted course with greater chances of eventuating in very serious sequellae. Similarly, the economic realities of the day prevent those who are already infected from accessing proper investigation and treatment. We may be heading towards an era of chronic liver disease epidemic.

Other parts of the gastrointestinal system are not spared. The incidence of colorectal cancer has been reported to be on the increase in Nigeria. The cost of screening, diagnosis and treatment of this dreaded killer is clearly not within the reach of most Nigerians. In fact, there are reports that majority of patients who attend hospitals these days are people with advanced and complicated cases. The examples illustrated above are just two out of numerous diseases of the gastrointestinal system that are ravaging the populace.

I want to seize this opportunity to call on Nigerian Governments (Federal, State and Local) to urgently take definite steps to stem the ugly trend. Health budgets should be increased to a level where basic medical needs of the most vulnerable segments of the society would be reasonably met. Urgent steps should be taken to make necessary vaccines available. Provision of drugs and other medical supplies needs urgent and special intervention. These would help reduce the impending epidemic of serious chronic digestive diseases.

Vol. 8 No. 2

December 2016

It is with great pleasure that I introduce our respected readers to this issue of NJGH. The editorial board has put together an assortment of thought-provoking papers, including a review article, original articles, a case report and abstracts presented at the 2016 Annual Scientific Conference of SOGHIN in Lagos.

There is a saying that “the more things change, the more they stay the same”. Few months ago, the Rome IV criteria for functional gastrointestinal disorders (FGID)1 was launched to replace Rome III which had been subsisting for ten years. Some of the changes that were made are actually not new, with the result that a see-saw phenomenon seems to be playing out. The review article in this issue of NJGH titled “Concepts and controversies in disorders of upper gastrointestinal tract” highlights some of the unresolved issues in functional and non-functional gastrointestinal disorders.

The discovery of Helicobacter pylori over 3 decades ago2 was a milestone in the understanding of acid-peptic disorders. Contributing to the subject, Abdel, et al used a polymerase chain reaction (PCR) technique to determine the association between various gastrointestinal symptoms and Helicobacter pylori infection of the stomach. Their findings are contained in this issue. In the same vein, Ndububa, et al contributed an article titled: The pattern of gastritis and Helicobacter pylori colonization of the stomach in Nigerian patients with dyspepsia.

Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections are major contributors to morbidity and mortality globally especially in Africa. Also, featured in this issue is a study by Adesina, et al which describes selected laboratory values in pregnant women with HIV-HCV infection.

Vol. 8 No. 1

June 2016

This issue highlights the many challenges to controlling the scourge of Viral Hepatitis in Africa: poor public and political awareness, lack of accurate data for action, vaccination coverage, diagnosis and treatment; proffers approaches to address the challenges, including the dire need to increase the awareness and training of health care workers on hepatitis B and C.

Nwabuaku, et al. demonstrated a high prevalence of minimal hepatic encephalopathy (HE) in subjects with chronic liver disease. Infection and occult GI bleeding were significant risk factors for HE in this cohort. Adoption of cognitive evaluation may allow early identification of this liver de-compensation thus enabling a more aggressive preventative strategy.

In patients with Sickle cell anaemia, intrahepatic sickling and iron overload may be responsible for liver enzyme derangements, irrespective of hepatitis status as documented by Odeghe, et al. Other interesting articles in this edition include the experience of a Hepato-biliary Surgical Unit and their laudable efforts to establish laparoscopic cholecystectomy for the management of acute cholecystitis and a case report describing the rare gastro-duodenal Crohn’s disease in a young man with upper GI bleeding.

Vol. 7 No. 2

December 2015

This landmark edition of the Nigerian Journal of Gastroenterology and Hepatology bears three practice guidelines. This is the culmination of a long process where a decision was made to review the pre existing guideline for Hepatitis B and C management and to develop three additional practice guidelines for management of GERD and Dyspepsia, Hepatocellular carcinoma and Colorectal cancer screening. Four committees comprising the nations foremost authorities in these areas were constituted during the Annual General Meeting of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN) held in Lagos in July 2013.

Vol. 7 No. 1

June 2015

In this edition, more clinical evidence is emerging in the area of Gastroenterology with the wider availability of endoscopic techniques in Nigeria. Akere, et. al identified gastric erosions as the commonest cause of acute upper gastrointestinal bleeding in Ibadan. Akintayo and Bojuwoye also report the finding of multiple angiodysplasia in the distal colon in a patient with the rare Osler- Weber-Rendu syndrome.

Other exciting highlights include identifying pregnant women with hepatitis B virus infection who may be at risk for mother-to-child HBV transmission. This article by Ogunlana is particularly important and highlights the need for routine antenatal HBV testing.Obaseki demonstrates convincingly that the use of pro-forma reporting ensures standardization and optimizes quality reporting in histopathology. The dissociation between the high prevalence of helicobacter infection and low incidence of gastric cancer- the African paradox is the subject of the review by Abdul Kareem and colleagues. The scientific abstracts presented at the recently concluded 8th SOGHIN AGM in Ilorin continue to showcase the rapidly expanding frontiers and the exciting growth of GI in the past year.

Vol. 6 Nos. 1 & 2

December 2014

In this edition, the importance of multi-disciplinary team (MDT) approach for cancer management is featured. Oguntunde et. al, highlight the need to set up and sustain MDTs as an essential cancer- management protocol and discuss the opportunities for and challenges against its use in Nigeria. Drug induced hepatotoxicity of anti-tuberculosis therapy in subjects with HIV infection is a real clinical challenge and is evaluated by Nnabuchi et al. The role of various commonly used local herbs in the development of hepatotoxicity has always been a moot point but unproven phenomenon. Odigwe et al, convincingly highlight the role of hepatotoxicity of Pausinystalia yohimbe bark extract (Burantashi), a local herb commonly used as an aphrodisiac.

In the newly established SOGHIN News Corner, we showcase the occasion of 2014 World Hepatitis Day Events, which took place in more than 28 locations in Nigeria. Community hepatitis testing was carried out in volunteers in 27 centers nationwide and over 7,500 people were screened for Hepatitis B and C. This opened up a previously unexplored opportunity for SOGHIN to carry out nationwide hepatitis data capture as part of a nationwide prevalence study.

About Us

The Nigerian Journal of Gastroenterology and Hepatology, is a quarterly publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), which publishes original research on the biology and diseases of the Gut, Liver, Pancreas, Peritoneum and Spleen both in humans and experimental animal models.

Our Office

Editorial Office
Gastroenterology Unit, Department of Medicine
University of Nigeria Teaching Hospital Ituku/Ozalla
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