original article

Vol. 10 No. 2


December 2018

— Nwokediuko SC, Adekanle O, Akere A, Olokoba A, Anyanechi C, Umar S, Maiyaki A, Ijoma U, Obienu O, Uhunmwangho A, Gideon A, Chinwe O, Ugochukwu N and Ndububa D


Background: Dyspepsia is a chronic symptom complex characterized by epigastric pain or burning, postprandial fullness or early satiation.Its prevalence and risk factors exhibit a geographical variation the world over. This study was designed to determine the prevalence of uninvestigated dyspepsia in Nigeria, a homogenous African population but with diverse cultures.

Methods: This was an observational and descriptive questionnaire-based study of adult Nigerians in which the dyspepsia module of Rome III diagnostic criteria for functional gastrointestinal disorders was administered to participants.

Results: Out of 3522 subjects who participated in the study across the country, 461 (13.09%) satisfied the diagnostic criteria for dyspepsia. Epigastric pain syndrome (EPS) was the predominant subtype, accounting for 41.43% while postprandial distress syndrome (PDS) and EPS-PDS overlap accounted for 34.71% and 23.86% respectively. Uninvestigated dyspepsia was more common in the Northern part of the country, compared to the South. Independent predictors of dyspepsia were cigarette smoking, tribe and use of Kola nut.

Conclusion: Dyspepsia is a very common medical problem in Nigeria, having a prevalence of 13% and being perhaps more common in the Northern part of the country. Epigastric pain syndrome is the predominant subtype. Its predictors include cigarette smoking, ethnic/cultural grouping and habitual use of Kolanut.


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