case reports

Vol. 10 No. 1

Primary Biliary Cirrhosis in a 37 Year Old Nigerian Male: A Case Report

June 2018

— Agbo II, Ugiagbe RA, Omuemu CE, Eboikpomwen JO, Sefia U, Egbo O, Eghaghe EP and Woghiren AO


The typical patient with primary biliary cirrhosis (PBC) is a middle aged woman presenting with fatigue, pruritus, and markedly elevated serum alkaline phosphatase (ALP) levels. PBC has a higher incidence and prevalence among Caucasians and Hispanics. We reported this case to reinforce the fact that the “rarities” in our environment may not be so uncommon after all. This article reports a case of PBC in a Nigerian man who
presented with pruritus, hyperpigmentation and jaundice. The patient met all 3 diagnostic criteria and responded remarkably to Ursodeoxycholic acid (UDCA) tablets.
Primary biliary cirrhosis would be an unusual diagnosis to consider in a young male of African descent. Data on PBC among Africans has remained scanty. A high index of suspicion is key in any patient presenting with jaundice, pruritus and cholestasis.

Keywords: Primary biliary cirrhosis, Male


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The Nigerian Journal of Gastroenterology and Hepatology, is a quarterly publication of the Society for Gastroenterology and Hepatology in Nigeria (SOGHIN), which publishes original research on the biology and diseases of the Gut, Liver, Pancreas, Peritoneum and Spleen both in humans and experimental animal models.

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